TRPV5 Recombinant Rabbit Monoclonal Antibody [JE62-37] — image 1 of 3

Product details

TRPV5 Recombinant Rabbit Monoclonal Antibody [JE62-37]

Catalog number HA720109

Price for HA720109

Size / count 100 µL

About this product

Transient receptor potential cation channel subfamily V member 5 is a calcium channel protein that in humans is encoded by the TRPV5 gene. The TRPV5 gene is a member of the transient receptor family and the TRPV subfamily. The calcium-selective channel, TRPV5, encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. Both TRPV5 and TRPV6 are expressed in kidney and intestinal epithelial cells. TRPV5 is mainly expressed in kidney epithelial cells, where it plays an important role in the reabsorption of Ca2+, whereas TRPV6 is mainly expressed in the intestine. The enzyme α-klotho increases kidney calcium reabsorption by stabilizing TPRV5. Klotho is a beta-glucuronidase-like enzyme that activates TRPV5 by removal of sialic acid.

Specifications

Catalog number: HA720109
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Calcium transport protein 2 antibody Calcium transporter 2 antibody CAT 2 antibody CAT2 antibody ECAC 1 antibody ECaC antibody ECaC1 antibody Epithelial calcium channel 1 antibody Osm 9 like TRP channel 3 antibody Osm-9-like TRP channel 3 antibody OTRPC 3 antibody OTRPC3 antibody Transient receptor potential cation channel subfamily V member 5 antibody TRPV 5 antibody TrpV5 antibody TRPV5_HUMAN antibody
Abbreviation: TRPV5
Swiss Prot: Q9NQA5 Human, P69744 Mouse, Q9JIP0 Rat
Cellular Locus: Apical cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human TRPV5 aa 1-150/729.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: SiHa cell lysate, HL-60 cell lysate, mouse kidney tissue lysate, mouse lung tissue lysate, rat kidney tissue lysates, human prostate carcinoma tissue, mouse small intestine tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:100-1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 83 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TRPV5 Recombinant Rabbit Monoclonal Antibody [JE62-37]?

The catalog number for TRPV5 Recombinant Rabbit Monoclonal Antibody [JE62-37] is HA720109.

What sizes are available for TRPV5 Recombinant Rabbit Monoclonal Antibody [JE62-37]?

TRPV5 Recombinant Rabbit Monoclonal Antibody [JE62-37] is available in the following size(s): 100 µL.

Is TRPV5 Recombinant Rabbit Monoclonal Antibody [JE62-37] in stock?

TRPV5 Recombinant Rabbit Monoclonal Antibody [JE62-37] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TRPV5 Recombinant Rabbit Monoclonal Antibody [JE62-37] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.