UQCRH Recombinant Rabbit Monoclonal Antibody [JE62-25]

About this product

Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.

Specifications

Catalog number

HA720113

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Complex III subunit 6 antibody Complex III subunit VIII antibody Cytochrome b c1 complex subunit 6 antibody Cytochrome b c1 complex subunit 6 mitochondrial antibody Cytochrome c1 non heme 11 kDa protein antibody High protein , mitochondrial antibody MGC111572 antibody Mitochondrial hinge protein antibody QCR 6 antibody QCR6 antibody Ubiquinol cytochrome c reductase complex 11 kDa protein antibody Ubiquinol cytochrome c reductase complex 11 kDa protein mitochondrial antibody Ubiquinol cytochrome c reductase complex III subunit VIII antibody Ubiquinol cytochrome c reductase hinge protein antibody ubiquinol-cytochrome c reductase hinge protein antibody UQCR8 antibody

Abbreviation

UQCRH

Swiss Prot

P07919 Human, P99028 Mouse, Q5M9I5 Rat

Cellular Locus

Mitochondrion inner membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human UQCRH aa 42-91/91.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

Saos-2 cell lysate, Huh7 cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, mouse stomach tissue lysate, human kidney tissue, human stomach tissue, human small intestine tissue, mouse small intestine tissue, rat bladder tissue, THP-1.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:400 ;FC: 1:500-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 11 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes