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![iFluor™ 594 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea81244/imageurl/ha720116f.webp)
Product details
Catalog number HA720116F
Price for HA720116F
Size / count 100 µL
Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Cytokeratin 17 functions to regulate cell growth and size through its interactions with the adaptor protein 14-3-3-sigma to mediate protein synthesis. Mutations in the gene encoding for Cytokeratin 17 lead to depressed protein translation and smaller sized skin keratinocytes, corresponding to decreased Akt/mTOR signaling activity. Cytokeratin 17 may be a useful marker for cervical stem cell identification, squamous cell carcinoma of the larynx, respiratory syncytial virus and transitional cell carcinomas of the human urinary tract.
The catalog number for iFluor™ 594 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] is HA720116F.
iFluor™ 594 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] is available in the following size(s): 100 µL.
iFluor™ 594 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] is currently made to order / not held in immediate stock. Contact us for lead time.
Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed,
Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
