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Product details

iFluor™ 594 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08]

Catalog number HA720124F

Price for HA720124F

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Size / count 100 µL

About this product

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins constitute up to 85% of a mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10-nm diameter filaments. Cytokeratins are useful markers of tissue differentiation, and they aid in the characterization of malignant tumors. Cytokeratin 1 is highly expressed in several malignancies including epithelioid hemangioendohtheliomas, angiosarcomas, schwannomas, epithelioid sarcomas and synodal sarcomas. The gene encoding human Cytokeratin 1 maps to chromosome 12q13.13. Mutations in the gene encoding human Cytokeratin 1 lead to abnormal filament associations and epidermolytic hyperkeratosis.

Specifications

Catalog number
HA720124F
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
67 kDa cytokeratin antibody CK-1 antibody CK1 antibody Cytokeratin-1 antibody Cytokeratin1 antibody EHK antibody EHK1 antibody Epidermolytic hyperkeratosis 1 antibody EPPK antibody Hair alpha protein antibody K1 antibody K2C1_HUMAN antibody Keratin antibody Keratin type II cytoskeletal 1 antibody Keratin-1 antibody Keratin1 antibody KRT 1 antibody Krt1 antibody KRT1A antibody NEPPK antibody type II cytoskeletal 1 antibody Type II keratin Kb1 antibody Type-II keratin Kb1 antibody
Abbreviation
CK-1, K1, KRT1
Swiss Prot
P04264 Human, P04104 Mouse, Q6IMF3 Rat
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within mouse Cytokeratin 1 aa 586-637.
Isotype
IgG
Conjugation
iFluor™ 594
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Tissue
Positive Control
Human skin tissue.
Concentration
1 mg/mL
Dilution
IF-Tissue: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
Molecular Weight
66 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for iFluor™ 594 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08]?

The catalog number for iFluor™ 594 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] is HA720124F.

What sizes are available for iFluor™ 594 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08]?

iFluor™ 594 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] is available in the following size(s): 100 µL.

Is iFluor™ 594 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] in stock?

iFluor™ 594 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] is currently made to order / not held in immediate stock. Contact us for lead time.

What is iFluor™ 594 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] used for?

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins constitute up to 85% of a mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differen

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

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