iFluor™ 488 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08]

Catalog number HA720127F

Price for HA720127F

Size / count 100 µL

About this product

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins constitute up to 85% of a mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10-nm diameter filaments. Cytokeratins are useful markers of tissue differentiation, and they aid in the characterization of malignant tumors. Cytokeratin 1 is highly expressed in several malignancies including epithelioid hemangioendohtheliomas, angiosarcomas, schwannomas, epithelioid sarcomas and synodal sarcomas. The gene encoding human Cytokeratin 1 maps to chromosome 12q13.13. Mutations in the gene encoding human Cytokeratin 1 lead to abnormal filament associations and epidermolytic hyperkeratosis.

Specifications

Catalog number: HA720127F
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 67 kDa cytokeratin antibody CK-1 antibody CK1 antibody Cytokeratin-1 antibody Cytokeratin1 antibody EHK antibody EHK1 antibody Epidermolytic hyperkeratosis 1 antibody EPPK antibody Hair alpha protein antibody K1 antibody K2C1_HUMAN antibody Keratin antibody Keratin type II cytoskeletal 1 antibody Keratin-1 antibody Keratin1 antibody KRT 1 antibody Krt1 antibody KRT1A antibody NEPPK antibody type II cytoskeletal 1 antibody Type II keratin Kb1 antibody Type-II keratin Kb1 antibody
Abbreviation: CK-1, K1, KRT1, KRTA
Swiss Prot: P04264 Human, P04104 Mouse, Q6IMF3 Rat
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within mouse Cytokeratin 1 aa 586-637.
Isotype: IgG
Conjugation: iFluor™ 488
Type: Recombinant Rabbit monoclonal Antibody
Applications: IF-Tissue
Positive Control: Human skin tissue.
Concentration: 1 mg/mL
Dilution: IF-Tissue: 1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
Molecular Weight: Predicted band size: 66 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for iFluor™ 488 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08]?

The catalog number for iFluor™ 488 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] is HA720127F.

What sizes are available for iFluor™ 488 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08]?

iFluor™ 488 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] is available in the following size(s): 100 µL.

Is iFluor™ 488 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] in stock?

iFluor™ 488 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] is currently made to order / not held in immediate stock. Contact us for lead time.

What is iFluor™ 488 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] used for?

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.