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![iFluor™ 488 Conjugated Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody [SN71-07] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea814b4/imageurl/ha720130f.webp)
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Product details
Catalog number HA720130F
Price for HA720130F
Size / count 100 µL
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins, which are useful markers of tissue differentiation, also aid in the characterization of malignant tumors. IL-1 and TNFα induce transcription of cytokeratin 6 in epidermal keratinocytes via the C/EBP β transcription factor. In humans, multiple isoforms of cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies.
The catalog number for iFluor™ 488 Conjugated Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody [SN71-07] is HA720130F.
iFluor™ 488 Conjugated Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody [SN71-07] is available in the following size(s): 100 µL.
iFluor™ 488 Conjugated Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody [SN71-07] is currently made to order / not held in immediate stock. Contact us for lead time.
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiat
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
