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![iFluor™ 488 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82a4b/imageurl/ha720138f.webp)
Product details
Catalog number HA720138F
Price for HA720138F
Size / count 100 µL
Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Cytokeratin 17 functions to regulate cell growth and size through its interactions with the adaptor protein 14-3-3-sigma to mediate protein synthesis. Mutations in the gene encoding for Cytokeratin 17 lead to depressed protein translation and smaller sized skin keratinocytes, corresponding to decreased Akt/mTOR signaling activity. Cytokeratin 17 may be a useful marker for cervical stem cell identification, squamous cell carcinoma of the larynx, respiratory syncytial virus and transitional cell carcinomas of the human urinary tract.
The catalog number for iFluor™ 488 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] is HA720138F.
iFluor™ 488 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] is available in the following size(s): 100 µL.
iFluor™ 488 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] is currently made to order / not held in immediate stock. Contact us for lead time.
Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed,
Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.
Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
