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![iFluor™ 488 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81664/imageurl/ha720139f.webp)
Product details
Catalog number HA720139F
Price for HA720139F
Size / count 100 µL
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. For example, Cytokeratins 10 and 13 are expressed highly in a subset of squamous cell carcinomas while Cytokeratin 18 is expressed in a majority of adenocarcinomas and basal cell carcinomas. Cytokeratin 18 contains two major phosphorylation sites on Ser 33 and Ser 52. Phosphorylation of Ser 18 is essential for the association of Cytokeratin 18 with 14-3-3 proteins and is involved in keratin organization and distribution.
The catalog number for iFluor™ 488 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07] is HA720139F.
iFluor™ 488 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07] is available in the following size(s): 100 µL.
iFluor™ 488 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07] is currently made to order / not held in immediate stock. Contact us for lead time.
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integri
Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.
A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.
Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.
