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![iFluor™ 647 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c90061270361ea827ac/imageurl/ha720141f.webp)
Product details
Catalog number HA720141F
Price for HA720141F
Size / count 100 µL
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins constitute up to 85% of a mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10-nm diameter filaments. Cytokeratins are useful markers of tissue differentiation, and they aid in the characterization of malignant tumors. Cytokeratin 1 is highly expressed in several malignancies including epithelioid hemangioendohtheliomas, angiosarcomas, schwannomas, epithelioid sarcomas and synodal sarcomas. The gene encoding human Cytokeratin 1 maps to chromosome 12q13.13. Mutations in the gene encoding human Cytokeratin 1 lead to abnormal filament associations and epidermolytic hyperkeratosis.
The catalog number for iFluor™ 647 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] is HA720141F.
iFluor™ 647 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] is available in the following size(s): 100 µL.
iFluor™ 647 Conjugated Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody [SN72-08] is currently made to order / not held in immediate stock. Contact us for lead time.
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins constitute up to 85% of a mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differen
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