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![iFluor™ 647 Conjugated Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody [SN71-07] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81c21/imageurl/ha720143f.webp)
Product details
Catalog number HA720143F
Price for HA720143F
Size / count 100 µL
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins, which are useful markers of tissue differentiation, also aid in the characterization of malignant tumors. IL-1 and TNFα induce transcription of cytokeratin 6 in epidermal keratinocytes via the C/EBP β transcription factor. In humans, multiple isoforms of cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies.
The catalog number for iFluor™ 647 Conjugated Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody [SN71-07] is HA720143F.
iFluor™ 647 Conjugated Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody [SN71-07] is available in the following size(s): 100 µL.
iFluor™ 647 Conjugated Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody [SN71-07] is currently made to order / not held in immediate stock. Contact us for lead time.
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiat
As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
