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Product details

iFluor™ 647 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05]

Catalog number HA720144F

Price for HA720144F

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Size / count 100 µL

About this product

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The a-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins are useful markers of tissue differentiation and, in addition, they aid in the characterization of malignant tumors. Cytokeratin 7 (also known as sarcolectin) agglutinates normal and transformed cells with a high affinity for simple sugars. Cytokeratin 7 also inhibits the synthesis of interferon-dependent secondary proteins thus reversing the antiviral effect of interferon induction and restoring cells to their status ad primum. In normal and transformed cells, Cytokeratin 7 localizes to the membrane.

Specifications

Catalog number
HA720144F
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CK 7 antibody CK-7 antibody CK7 antibody Cytokeratin 7 antibody Cytokeratin-7 antibody D15Wsu77e antibody K2C7 antibody K2C7_HUMAN antibody K7 antibody Keratin 7 antibody Keratin 7, type II antibody Keratin type II cytoskeletal 7 antibody Keratin, 55K type II cytoskeletal antibody Keratin, simple epithelial antibody Keratin, simple epithelial type I, K7 antibody Keratin, type II cytoskeletal 7 antibody Keratin-7 antibody Krt2-7 antibody KRT7 antibody MGC11625 antibody MGC129731 antibody MGC3625 antibody Sarcolectin antibody SCL antibody Type II mesothelial keratin K7 antibody Type-II keratin Kb7 antibody Cytokeratin7
Abbreviation
CK-7, K7, KRT7, SCL
Swiss Prot
P08729 Human, Q9DCV7 Mouse
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within Human Cytokeratin 7 aa 18-67.
Isotype
IgG
Conjugation
iFluor™ 647
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Cell, IF-Tissue, FC
Positive Control
SK-Br-3, human liver tissue, human breast tissue.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:100 ;IF-Tissue: 1:50-1:200 ;FC: 1ug/mL
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.
Molecular Weight
Predicted band size: 51 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for iFluor™ 647 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05]?

The catalog number for iFluor™ 647 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05] is HA720144F.

What sizes are available for iFluor™ 647 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05]?

iFluor™ 647 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05] is available in the following size(s): 100 µL.

Is iFluor™ 647 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05] in stock?

iFluor™ 647 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05] is currently made to order / not held in immediate stock. Contact us for lead time.

What is iFluor™ 647 Conjugated Cytokeratin 7 Recombinant Rabbit Monoclonal Antibody [ST50-05] used for?

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiat

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

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