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Product details

iFluor™ 647 Conjugated Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody [SC52-09]

Catalog number HA720149F

Price for HA720149F

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Size / count 100 µL

About this product

Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in noninvasive breast carcinomas and normal breast tissue. Mutations in the Cytokeratin 16 gene cause various diseases, including pachyonychia congenita type 1 (PC1), nonepidermolytic palmoplantar keratoderma (NEPPK) and unilateral palmoplantar verrucous nevus (UPVN).

Specifications

Catalog number
HA720149F
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CK 16 antibody CK-16 antibody CK16 antibody Cytokeratin-16 antibody Cytokeratin16 antibody FNEPPK antibody Focal non epidermolytic palmoplantar keratoderma antibody K 16 antibody K16 antibody K1C16_HUMAN antibody K1CP antibody Keratin 1 type I antibody Keratin 16 antibody Keratin antibody Keratin type I cytoskeletal 16 antibody Keratin-16 antibody Keratin16 antibody KRT 16 antibody Krt16 antibody KRT16A antibody NEPPK antibody PC1 antibody type I cytoskeletal 16 antibody
Abbreviation
CK-16, K16, KRT16A
Swiss Prot
P08779 Human
Cellular Locus
Cytoskeleton, Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human Cytokeratin 16 aa 27-75.
Isotype
IgG
Conjugation
iFluor™ 647
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Tissue
Positive Control
Human skin tissue, human esophagus tissue.
Concentration
1 mg/mL
Dilution
IF-Tissue: 1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
Molecular Weight
Predicted band size: 51 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for iFluor™ 647 Conjugated Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody [SC52-09]?

The catalog number for iFluor™ 647 Conjugated Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody [SC52-09] is HA720149F.

What sizes are available for iFluor™ 647 Conjugated Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody [SC52-09]?

iFluor™ 647 Conjugated Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody [SC52-09] is available in the following size(s): 100 µL.

Is iFluor™ 647 Conjugated Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody [SC52-09] in stock?

iFluor™ 647 Conjugated Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody [SC52-09] is currently made to order / not held in immediate stock. Contact us for lead time.

What is iFluor™ 647 Conjugated Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody [SC52-09] used for?

Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall stru

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

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