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![iFluor™ 647 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82c2b/imageurl/ha720150f.webp)
Product details
Catalog number HA720150F
Price for HA720150F
Size / count 100 µL
Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Cytokeratin 17 functions to regulate cell growth and size through its interactions with the adaptor protein 14-3-3-sigma to mediate protein synthesis. Mutations in the gene encoding for Cytokeratin 17 lead to depressed protein translation and smaller sized skin keratinocytes, corresponding to decreased Akt/mTOR signaling activity. Cytokeratin 17 may be a useful marker for cervical stem cell identification, squamous cell carcinoma of the larynx, respiratory syncytial virus and transitional cell carcinomas of the human urinary tract.
The catalog number for iFluor™ 647 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] is HA720150F.
iFluor™ 647 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] is available in the following size(s): 100 µL.
iFluor™ 647 Conjugated Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody [SR45-06] is currently made to order / not held in immediate stock. Contact us for lead time.
Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed,
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
