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Product details

iFluor™ 647 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07]

Catalog number HA720151F

Price for HA720151F

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Size / count 100 µL

About this product

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 18 is a type I cytokeratin. It is, together with its filament partner Cytokeratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Keratin 18 is often used together with Cytokeratin 8 and Cytokeratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

Specifications

Catalog number
HA720151F
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Cell proliferation inducing gene 46 protein antibody Cell proliferation inducing protein 46 antibody Cell proliferation-inducing gene 46 protein antibody CK 18 antibody CK-18 antibody CK18 antibody CYK 18 antibody CYK18 antibody Cytokeratin 18 antibody Cytokeratin endo B antibody Cytokeratin-18 antibody K 18 antibody K18 antibody K1C18_HUMAN antibody KA18 antibody Keratin 18 antibody Keratin 18, type I antibody Keratin D antibody keratin, type I cytoskeletal 18 antibody Keratin-18 antibody Krt18 antibody
Abbreviation
CK-18, K18, KRT18, CYK18
Swiss Prot
P05783 Human, P05784 Mouse, Q5BJY9 Rat
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within mouse Cytokeratin 18 aa 200-423.
Isotype
IgG
Conjugation
iFluor™ 647
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Tissue
Positive Control
Human liver tissue.
Concentration
1 mg/mL
Dilution
IF-Tissue: 1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
Molecular Weight
Predicted band size: 48 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for iFluor™ 647 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07]?

The catalog number for iFluor™ 647 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07] is HA720151F.

What sizes are available for iFluor™ 647 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07]?

iFluor™ 647 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07] is available in the following size(s): 100 µL.

Is iFluor™ 647 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07] in stock?

iFluor™ 647 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is iFluor™ 647 Conjugated Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody [SZ80-07] used for?

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integri

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

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