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Product details

iFluor™ 647 Conjugated Cytokeratin 19 Recombinant Rabbit Monoclonal Antibody [SA30-06]

Catalog number HA720152F

Price for HA720152F

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Size / count 100 µL

About this product

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells and have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. For example, many types of cancer cells express Cytokeratin 19 (CK19), an epithelial cytoskeletal protein within the suprabasal squamous epithelium. Cytokeratin 19 is a specific marker of moderate to severe dysplasia and carcinoma in situ in oral cavity squamous epithelium, and measurement of Cytokeratin 19 may be a useful marker in diagnosing hepatoma. Cytokeratin 19 fragment levels in serum have been documented as a marker for lung cancer. Clinical investigations have suggested that serum CYFRA 21-1, a fragment of Cytokeratin 19, may be among the most useful tumor markers.

Specifications

Catalog number
HA720152F
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
40 kDa keratin intermediate filament antibody CK 19 antibody CK-19 antibody CK19 antibody Cytokeratin 19 antibody Cytokeratin-19 antibody K19 antibody K1C19_HUMAN antibody K1CS antibody Keratin 19 antibody Keratin type I 40 kD antibody Keratin type I 40kD antibody Keratin type I cytoskeletal 19 antibody Keratin, type I cytoskeletal 19 antibody Keratin, type I, 40 kd antibody Keratin-19 antibody KRT19 antibody MGC15366 antibody
Abbreviation
CK-19, K19, KRT19
Swiss Prot
P08727 Human, P19001 Mouse
Cellular Locus
Cytoskeleton.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within Human Cytokeratin 19 aa 348-400.
Isotype
IgG
Conjugation
iFluor™ 647
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Cell, IF-Tissue, FC
Positive Control
SK-Br-3, human liver tissue, human breast tissue, human kidney tissue, MCF-7.
Concentration
1 mg/mL
Dilution
IF-Cell: 1:100 ;IF-Tissue: 1:50-1:100 ;FC: 1 ug/mL
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
Molecular Weight
Predicted band size: 44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for iFluor™ 647 Conjugated Cytokeratin 19 Recombinant Rabbit Monoclonal Antibody [SA30-06]?

The catalog number for iFluor™ 647 Conjugated Cytokeratin 19 Recombinant Rabbit Monoclonal Antibody [SA30-06] is HA720152F.

What sizes are available for iFluor™ 647 Conjugated Cytokeratin 19 Recombinant Rabbit Monoclonal Antibody [SA30-06]?

iFluor™ 647 Conjugated Cytokeratin 19 Recombinant Rabbit Monoclonal Antibody [SA30-06] is available in the following size(s): 100 µL.

Is iFluor™ 647 Conjugated Cytokeratin 19 Recombinant Rabbit Monoclonal Antibody [SA30-06] in stock?

iFluor™ 647 Conjugated Cytokeratin 19 Recombinant Rabbit Monoclonal Antibody [SA30-06] is currently made to order / not held in immediate stock. Contact us for lead time.

What is iFluor™ 647 Conjugated Cytokeratin 19 Recombinant Rabbit Monoclonal Antibody [SA30-06] used for?

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integri

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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