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![iFluor™ 488 Conjugated CCR7 Recombinant Rabbit Monoclonal Antibody [SR36-04] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea818cc/imageurl/ha720157f.webp)
Product details
Catalog number HA720157F
Price for HA720157F
Size / count 100 µL
C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. Two ligands have been identified for this receptor: the chemokines (C-C motif) ligand 19 (CCL19/ELC) and (C-C motif) ligand 21 (CCL21). CCR7 has also recently been designated CD197 (cluster of differentiation 197). The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein–Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. CCR7 has been shown to stimulate dendritic cell maturation. CCR7 is also involved in homing of T cells to various secondary lymphoid organs such as lymph nodes and the spleen as well as trafficking of T cells within the spleen. Activation of dendritic cells in peripheral tissues induces CCR7 expression on the cell's surface, which recognize CCL19 and CCL21 produced in the Lymph node and increases dendritic cell expression of co-stimulation molecules (B7), and MHC class I or MHC class II.
The catalog number for iFluor™ 488 Conjugated CCR7 Recombinant Rabbit Monoclonal Antibody [SR36-04] is HA720157F.
iFluor™ 488 Conjugated CCR7 Recombinant Rabbit Monoclonal Antibody [SR36-04] is available in the following size(s): 100 µL.
iFluor™ 488 Conjugated CCR7 Recombinant Rabbit Monoclonal Antibody [SR36-04] is currently made to order / not held in immediate stock. Contact us for lead time.
C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. Two ligands have been identified for this receptor: the chemokines (C-C motif) ligand 19 (CCL19/ELC) and (C-C motif) ligand 21 (CCL21). CCR7 has also recently been designated CD197 (cluster of differentiation 197)
Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.
Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
