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![iFluor™ 647 Conjugated Glucose Transporter GLUT1 Recombinant Rabbit Monoclonal Antibody [SA0377] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81818/imageurl/ha720170f.webp)
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Product details
Catalog number HA720170F
Price for HA720170F
Size / count 100 µL
Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter, Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane, and shows a much less dramatic translocation in response to insulin. Glut1 and Glut4 are twelve-pass transmembrane proteins (12TM) whose carboxy-termini may dictate their cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity.
The catalog number for iFluor™ 647 Conjugated Glucose Transporter GLUT1 Recombinant Rabbit Monoclonal Antibody [SA0377] is HA720170F.
iFluor™ 647 Conjugated Glucose Transporter GLUT1 Recombinant Rabbit Monoclonal Antibody [SA0377] is available in the following size(s): 100 µL.
iFluor™ 647 Conjugated Glucose Transporter GLUT1 Recombinant Rabbit Monoclonal Antibody [SA0377] is currently made to order / not held in immediate stock. Contact us for lead time.
Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the r
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
