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![iFluor™ 647 Conjugated Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81ace/imageurl/ha720172f.webp)
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Product details
Catalog number HA720172F
Price for HA720172F
Size / count 100 µL
A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
The catalog number for iFluor™ 647 Conjugated Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07] is HA720172F.
iFluor™ 647 Conjugated Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07] is available in the following size(s): 100 µL.
iFluor™ 647 Conjugated Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07] is currently made to order / not held in immediate stock. Contact us for lead time.
A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins whic
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.
