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Product details

iFluor™ 647 Conjugated SATB2 Recombinant Rabbit Monoclonal Antibody [JM52-44]

Catalog number HA720173F

Price for HA720173F

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Size / count 100 µL

About this product

SATB2 (Special AT-rich sequence-binding protein 2) is a nuclear matrix protein that influences craniofacial formation mechanisms, such as jaw and palate development, and is part of a transcriptional network regulating skeletal development and osteoblast differentiation. Highly expressed in adult and fetal brain, SATB2 contains two CUT DNA-binding domains and one homeobox domain and is closely related to SATB1, a transcriptional repressor. SATB2 is thought to bind to matrix-attachment regions (MARs) and regulate MAR-dependent transcription of various genes, including HoxA2 and ATF4 (CREB-2), involved in skeletal development. Functioning as both a transcriptional activator and repressor, SATB2 can also act as a protein scaffold that can enhance the activity of other DNA-binding proteins. Defects in the gene encoding SATB2 are the cause of cleft palate manifested in conjunction with severe mental retardation.

Specifications

Catalog number
HA720173F
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
DNA binding protein SATB2 antibody DNA-binding protein SATB2 antibody FLJ21474 antibody FLJ32076 antibody GLSS antibody KIAA1034 antibody MGC119474 antibody MGC119477 antibody SATB family member 2 antibody SATB homeobox 2 antibody SATB2 antibody SATB2_HUMAN antibody Special AT rich sequence binding protein 2 antibody Special AT-rich sequence-binding protein 2 antibody
Abbreviation
SATB2, KIAA1034
Swiss Prot
Q9UPW6 Human
Cellular Locus
Nucleus matrix.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human SATB2 238-287 / 733.
Isotype
IgG
Conjugation
iFluor™ 647
Type
Recombinant Rabbit monoclonal Antibody
Applications
IF-Tissue, FC
Positive Control
Human colon carcinoma tissue, THP-1.
Concentration
1 mg/mL
Dilution
IF-Tissue: 1:200;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
Molecular Weight
Predicted band size: 83 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

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