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![GNA13 Recombinant Rabbit Monoclonal Antibody [JE63-76] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80d82/imageurl/ha721007.webp)
Product details
Catalog number HA721007
Price for HA721007
Size / count 100 µL
Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13 gene. The GNA13 gene encodes the G13 G protein alpha subunit. Together with GNA12, these two proteins comprise one of the four classes of heterotrimeric G protein alpha subunits. Heterotrimeric G proteins function in transducing hormone and neurotransmitter signals detected by cell surface G protein-coupled receptors to intracellular signaling pathways to modulate cell functions. G protein alpha subunits bind to guanine nucleotides and function in a regulatory cycle, and are active when bound to GTP but inactive and associated with the G beta-gamma complex when bound to GDP. Active GTP-bound G12 alpha subunit interacts with and activates ARHGEF1, ARHGEF11, and ARHGEF12. These ARHGEF proteins function as guanine nucleotide exchange factors for the Rho small GTPases to regulate the actin cytoskeleton. GNA13 has been shown to interact with AKAP3, RIC8A, and Radixin. Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma.
The catalog number for GNA13 Recombinant Rabbit Monoclonal Antibody [JE63-76] is HA721007.
GNA13 Recombinant Rabbit Monoclonal Antibody [JE63-76] is available in the following size(s): 100 µL.
GNA13 Recombinant Rabbit Monoclonal Antibody [JE63-76] is currently made to order / not held in immediate stock. Contact us for lead time.
Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13 gene. The GNA13 gene encodes the G13 G protein alpha subunit. Together with GNA12, these two proteins comprise one of the four classes of heterotrimeric G protein alpha subunits. Heterotrimeric G
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
