ATG4A Recombinant Rabbit Monoclonal Antibody [JE32-31]

About this product

Cysteine protease ATG4A is an enzyme that in humans is encoded by the ATG4A gene. Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodelling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

Specifications

Catalog number

HA721010

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

AI627006 antibody APG4 autophagy 4 homolog A antibody Apg4a antibody ATG4 autophagy related 4 homolog A (S. cerevisiae) antibody ATG4 autophagy related 4 homolog A antibody ATG4A antibody ATG4A_HUMAN antibody Atg4al antibody AUT like 2 cysteine endopeptidase antibody AUT-like 2 cysteine endopeptidase antibody Autl2 antibody Autophagin 2 antibody Autophagin-2 antibody Autophagy related 4A cysteine peptidase antibody Autophagy related cysteine endopeptidase 2 antibody Autophagy related protein 4 homolog A antibody Autophagy-related cysteine endopeptidase 2 antibody Autophagy-related protein 4 homolog A antibody AV169859 antibody Cysteine protease ATG4A antibody hAPG4A antibody MGC107179 antibody

Abbreviation

ATG4A

Swiss Prot

Q8WYN0 Human, Q8C9S8 Mouse, B1H274 Rat

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human ATG4A aa 1-50/398.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC, IF-Cell

Positive Control

K562 cell lysate, Jurkat cell lysate, mouse kidney tissue lysate, rat kidney tissue lysate, human testis tissue, human striated muscle tissue, mouse kidney tissue, PC-3M, Hela.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:100-1:400 ;FC: 1:500-1:1,000 ;IF-Cell: 1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 45 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes