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Product details

P2Y12 Recombinant Rabbit Monoclonal Antibody [JE63-23]

Catalog number HA721011

Price for HA721011

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Size / count 100 µL

About this product

P2Y12 is a chemoreceptor for adenosine diphosphate (ADP) that belongs to the Gi class of a group of G protein-coupled (GPCR) purinergic receptors. This P2Y receptor family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. The P2Y12 receptor is involved in platelet aggregation and is thus a biological target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. In the field of purinergic signaling, the P2Y12 protein on the periphery is found mainly but not exclusively on the surface of blood platelets, and is an important regulator in blood clotting. In the central nervous system, this receptor has been found expressed exclusively on microglia, where it is necessary for physiological and pathological microglial actions, such as monitoring neuronal functions and microglial neuroprotection.

Specifications

Catalog number
HA721011
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ADP glucose receptor antibody ADP-glucose receptor antibody ADPG R antibody ADPG-R antibody ADPGR antibody BDPLT8 antibody G protein coupled receptor SP1999 antibody Gi coupled ADP receptor HORK 3 antibody Gi coupled ADP receptor HORK3 antibody HORK 3 antibody HORK3 antibody P2RY 12 antibody P2RY12 antibody P2T (AC) antibody P2Y 12 antibody P2Y purinoceptor 12 antibody P2Y (12)R antibody P2Y (AC) antibody P2Y (ADP) antibody P2Y (cyc) antibody P2Y12 antibody P2Y12 platelet ADP receptor antibody P2Y12_HUMAN antibody Platelet ADP receptor antibody Purinergic receptor P2RY12 antibody Purinergic receptor P2Y G protein coupled 12 antibody Purinergic receptor P2Y12 antibody Putative G protein coupled receptor antibody SP 1999 antibody SP1999 antibody
Abbreviation
P2RY12
Swiss Prot
Q9H244 Human, Q9CPV9 Mouse
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within human P2Y12 aa 101-342/342.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
NIH/3T3 cell lysate, PC-3 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 39 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for P2Y12 Recombinant Rabbit Monoclonal Antibody [JE63-23]?

The catalog number for P2Y12 Recombinant Rabbit Monoclonal Antibody [JE63-23] is HA721011.

What sizes are available for P2Y12 Recombinant Rabbit Monoclonal Antibody [JE63-23]?

P2Y12 Recombinant Rabbit Monoclonal Antibody [JE63-23] is available in the following size(s): 100 µL.

Is P2Y12 Recombinant Rabbit Monoclonal Antibody [JE63-23] in stock?

P2Y12 Recombinant Rabbit Monoclonal Antibody [JE63-23] is currently made to order / not held in immediate stock. Contact us for lead time.

What is P2Y12 Recombinant Rabbit Monoclonal Antibody [JE63-23] used for?

P2Y12 is a chemoreceptor for adenosine diphosphate (ADP) that belongs to the Gi class of a group of G protein-coupled (GPCR) purinergic receptors. This P2Y receptor family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine an

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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