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Product details

DENN Recombinant Rabbit Monoclonal Antibody [JE63-62]

Catalog number HA721022

Price for HA721022

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Size / count 100 µL

About this product

MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.

Specifications

Catalog number
HA721022
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Differentially expressed in normal and neoplastic cells antibody FLJ35600 antibody IG20 antibody Insulinoma glucagonoma clone 20 antibody KIAA0358 antibody MADD antibody MADD_HUMAN antibody MAP kinase-activating death domain protein antibody Rab3 GDP/GTP exchange factor antibody RAB3GEP antibody DENN
Abbreviation
MADD
Swiss Prot
Q8WXG6 Human
Cellular Locus
Cell membrane, cytoplasm, axon.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within human DENN aa 1,598-1,647/1,647.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HepG2 cell lysate, Hela cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 183 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for DENN Recombinant Rabbit Monoclonal Antibody [JE63-62]?

The catalog number for DENN Recombinant Rabbit Monoclonal Antibody [JE63-62] is HA721022.

What sizes are available for DENN Recombinant Rabbit Monoclonal Antibody [JE63-62]?

DENN Recombinant Rabbit Monoclonal Antibody [JE63-62] is available in the following size(s): 100 µL.

Is DENN Recombinant Rabbit Monoclonal Antibody [JE63-62] in stock?

DENN Recombinant Rabbit Monoclonal Antibody [JE63-62] is currently made to order / not held in immediate stock. Contact us for lead time.

What is DENN Recombinant Rabbit Monoclonal Antibody [JE63-62] used for?

MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytop

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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