Product details
Catalog number HA721029
Price for HA721029
Size / count 100 µL
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
The catalog number for Cip4 Recombinant Rabbit Monoclonal Antibody [JE63-45] is HA721029.
Cip4 Recombinant Rabbit Monoclonal Antibody [JE63-45] is available in the following size(s): 100 µL.
Cip4 Recombinant Rabbit Monoclonal Antibody [JE63-45] is currently made to order / not held in immediate stock. Contact us for lead time.
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylseri
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Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
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