IL-23 Recombinant Rabbit Monoclonal Antibody [JE38-99] — image 1 of 3

Product details

IL-23 Recombinant Rabbit Monoclonal Antibody [JE38-99]

Catalog number HA721037

Price for HA721037

Size / count 100 µL

About this product

This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4 (+) T cells, IL23 preferentially acts on memory CD4 (+) T cells. Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Specifications

Catalog number: HA721037
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: IL 23 A antibody IL 23 antibody IL 23 subunit alpha antibody IL 23A antibody IL 23p19 antibody IL-23 subunit alpha antibody IL-23-A antibody IL-23p19 antibody IL12B antibody IL23 antibody Il23a antibody IL23A_HUMAN antibody IL23P19 antibody interleukin 12B antibody Interleukin 23 alpha subunit p19 antibody Interleukin 23 p19 subunit antibody interleukin 23 subunit alpha antibody interleukin 23 subunit p19 antibody interleukin six, G CSF related factor antibody Interleukin-23 subunit alpha antibody Interleukin-23 subunit p19 antibody JKA3 induced upon T cell activation antibody MGC79388 antibody P19 antibody SGRF antibody
Abbreviation: IL23A
Swiss Prot: Q9NPF7 Human
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human IL23 100-189.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Daudi cell lysates, THP-1 cell lysate, Raji cell lysate, human lymph nodes tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:400
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 21 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for IL-23 Recombinant Rabbit Monoclonal Antibody [JE38-99]?

The catalog number for IL-23 Recombinant Rabbit Monoclonal Antibody [JE38-99] is HA721037.

What sizes are available for IL-23 Recombinant Rabbit Monoclonal Antibody [JE38-99]?

IL-23 Recombinant Rabbit Monoclonal Antibody [JE38-99] is available in the following size(s): 100 µL.

Is IL-23 Recombinant Rabbit Monoclonal Antibody [JE38-99] in stock?

IL-23 Recombinant Rabbit Monoclonal Antibody [JE38-99] is currently made to order / not held in immediate stock. Contact us for lead time.

What is IL-23 Recombinant Rabbit Monoclonal Antibody [JE38-99] used for?

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.