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Product details

ITPK1 Recombinant Rabbit Monoclonal Antibody [JE64-35]

Catalog number HA721039

Price for HA721039

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Size / count 100 µL

About this product

This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X. Plays an important role in MLKL-mediated necroptosis. Produces highly phosphorylated inositol phosphates such as inositolhexakisphosphate (InsP6) which bind to MLKL mediating the release of an N-terminal auto-inhibitory region leading to its activation. Essential for activated phospho-MLKL to oligomerize and localize to the cell membrane during necroptosis.

Specifications

Catalog number
HA721039
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
3 antibody 4)P (3) 5/6-kinase antibody 4-trisphosphate 5/6-kinase antibody Inositol 1 3 4 triphosphate 5/6 kinase antibody Inositol 1 3 4 trisphosphate 5/6 kinase antibody Inositol 1 antibody Inositol tetrakisphosphate 1 kinase antibody Inositol triphosphate 5/6 kinase antibody Inositol-tetrakisphosphate 1-kinase antibody Inositol-triphosphate 5/6-kinase antibody Ins (1 3 4)P (3) 5/6 kinase antibody Ins (1 antibody ITPK 1 antibody itpk1 antibody ITPK1_HUMAN antibody ITRPK 1 antibody ITRPK1 antibody
Abbreviation
ITPK1
Swiss Prot
Q13572 Human
Cellular Locus
Cytosol, apical plasma membrane, cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human ITPK1 aa 362-410.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Hela cell lysate, HepG2 cell lysate, 293T cell lysate, A431 cell lysate, MCF-7 cell lysate, human liver tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 46 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for ITPK1 Recombinant Rabbit Monoclonal Antibody [JE64-35]?

The catalog number for ITPK1 Recombinant Rabbit Monoclonal Antibody [JE64-35] is HA721039.

What sizes are available for ITPK1 Recombinant Rabbit Monoclonal Antibody [JE64-35]?

ITPK1 Recombinant Rabbit Monoclonal Antibody [JE64-35] is available in the following size(s): 100 µL.

Is ITPK1 Recombinant Rabbit Monoclonal Antibody [JE64-35] in stock?

ITPK1 Recombinant Rabbit Monoclonal Antibody [JE64-35] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ITPK1 Recombinant Rabbit Monoclonal Antibody [JE64-35] used for?

This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of th

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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