TRIM24 Recombinant Rabbit Monoclonal Antibody [JE64-31]

About this product

Tripartite motif-containing 24 (TRIM24) also known as transcriptional intermediary factor 1α (TIF1α) is a protein that, in humans, is encoded by the TRIM24 gene. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains – a RING, a B-box type 1 and a B-box type 2 – and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. TRIM24 has been shown to interact with Mineralocorticoid receptor, TRIM33, Estrogen receptor alpha and Retinoid X receptor alpha.

Specifications

Catalog number

HA721052

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

E3 ubiquitin protein ligase TRIM24 antibody E3 ubiquitin-protein ligase Trim24 antibody hTIF1 antibody PTC6 antibody RING finger protein 82 antibody RNF82 antibody TF1A antibody TIF1 alpha antibody TIF1 antibody TIF1-alpha antibody TIF1A antibody TIF1A_HUMAN antibody TIF1ALPHA antibody Transcription intermediary factor 1-alpha antibody Transcriptional intermediary factor 1 alpha antibody Transcriptional intermediary factor 1 antibody Trim24 antibody Tripartite motif containing 24 antibody Tripartite motif-containing protein 24 antibody

Abbreviation

TRIM24

Swiss Prot

O15164 Human

Cellular Locus

Nucleus, Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within human TRIM24 aa 405-455/1,050.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

HepG2 cell lysate, HeLa cell lysate, human bladder carcinoma tissue, human breast carcinoma tissue, human thyroid tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:400-1:2,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 117 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes