Adiponectin Recombinant Rabbit Monoclonal Antibody [JE65-49]

About this product

Adiponectin (also referred to as GBP-28, apM1, AdipoQ and Acrp30) is a protein hormone and adipokine, which is involved in regulating glucose levels as well as fatty acid breakdown. In humans it is encoded by the ADIPOQ gene and it is produced in primarily in adipose tissue, but also in muscle, and even in the brain. Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation. Transgenic mice with increased adiponectin show reduced adipocyte differentiation and increased energy expenditure associated with mitochondrial uncoupling. Adiponectin is secreted into the bloodstream where it accounts for approximately 0.01% of all plasma protein at around 5-10 μg/mL (mg/L). Adiponectin automatically self-associates into larger structures. Initially, three adiponectin molecules bind together to form a homotrimer. Adiponectin exerts some of its weight reduction effects via the brain. This is similar to the action of leptin; adiponectin and leptin can act synergistically. Adiponectin promoted synaptic and memory function in the brain. Humans with lower levels of adiponectin have reduced cognitive function.

Specifications

Catalog number

HA721064

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

30 kDa adipocyte complement related protein antibody 30 kDa adipocyte complement-related protein antibody ACDC antibody Acrp 30 antibody ACRP30 antibody ADIPO_HUMAN antibody Adipocyte antibody Adipocyte C1q and collagen domain containing protein antibody Adipocyte complement related 30 kDa protein antibody Adipocyte complement related protein of 30 kDa antibody Adipocyte complement-related 30 kDa protein antibody adipocyte-specific secretory protein antibody Adiponectin antibody Adiponectin precursor antibody adiponectin, C1Q and collagen domain containing antibody Adipoq antibody Adipose most abundant gene transcript 1 antibody Adipose most abundant gene transcript 1 protein antibody Adipose specific collagen like factor antibody ADIPQTL1 antibody ADPN antibody APM 1 antibody apM-1 antibody APM1 antibody C1q and collagen domain-containing protein antibody GBP 28 antibody GBP28 antibody Gelatin binding protein antibody Gelatin binding protein 28 antibody gelatin-binding protein 28 antibody Gelatin-binding protein antibody OTTHUMP00000210047 antibody

Abbreviation

Adipoq

Swiss Prot

Q60994 Mouse

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant protein within mouse Adiponectin aa 1-247/247.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

Mouse colon tissue lysates, mouse heart tissue lysates, Mouse white adipose lysate, Mouse brown adipose tissue lysate, NCI-H441, mouse colon tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:50 ;IHC-P: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 27 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes