SSX2IP Recombinant Rabbit Monoclonal Antibody [JE65-50]

About this product

Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin. Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling. Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Involved in ciliogenesis. It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia.

Specifications

Catalog number

HA721065

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

ADIP antibody ADIP_HUMAN antibody Afadin and alpha actinin binding protein antibody Afadin DIL domain interacting protein antibody Afadin DIL domain-interacting protein antibody Afadin- and alpha-actinin-binding protein antibody FLJ10848 antibody KIAA0923 antibody MGC75026 antibody OTTHUMP00000011574 antibody SSX 2 interacting protein antibody SSX2 interacting protein antibody SSX2-interacting protein antibody SSX2IP antibody Synovial sarcoma X breakpoint 2 interacting protein antibody"

Abbreviation

SSX2IP

Swiss Prot

Q9Y2D8 Human

Cellular Locus

Centriolar satellite, cilium basal body, nucleus, adherens junction.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within human SLC25A12 aa 565-614/614.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB

Positive Control

Daudi cell lysate, K562 cell lysate.

Concentration

1 mg/mL

Dilution

WB: 1:500

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 71 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes