SLC25A12 Recombinant Rabbit Monoclonal Antibody [JE65-52]

About this product

This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. SLC25A12 (Solute Carrier Family 25 Member 12) is a Protein Coding gene. Diseases associated with SLC25A12 include Developmental And Epileptic Encephalopathy 39 and Citrullinemia, Type Ii, Adult-Onset. Among its related pathways are Glycosaminoglycan metabolism and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include calcium ion binding and L-aspartate transmembrane transporter activity. An important paralog of this gene is SLC25A13. Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.

Specifications

Catalog number

HA721066

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

AGC1 antibody Araceli hiperlarga antibody ARALAR antibody ARALAR1 antibody Calcium binding mitochondrial carrier superfamily member antibody Calcium binding mitochondrial carrier superfamily member Aralar1 antibody Calcium-binding mitochondrial carrier protein Aralar1 antibody CMC1_HUMAN antibody Mitochondrial aspartate glutamate carrier 1 antibody SLC25A12 antibody Solute carrier family 25 (aspartate/glutamate carrier) member 12 antibody Solute carrier family 25 (mitochondrial carrier Aralar) member 12 antibody Solute carrier family 25 member 12 antibody solute carrier family 25, member 12 antibody

Abbreviation

SLC25A12

Swiss Prot

O75746 Human, Q8BH59 Mouse,

Cellular Locus

Mitochondrion inner membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human SLC25A12 aa 601-650/678.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Hela cell lysate, Raji cell lysate, RAW264.7 cell lysate, rat kidney tissue lysate, human kidney tissue, mouse heart tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 75 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes