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Product details

GRSF1 Recombinant Rabbit Monoclonal Antibody [JE65-34]

Catalog number HA721076

Price for HA721076

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Size / count 100 µL

About this product

The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences. Involved in the degradosome-mediated decay of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. Acts by unwinding G-quadruplex RNA structures in MT-ncRNA, thus facilitating their degradation by the degradosome. G-quadruplexes (G4) are non-canonical 4 stranded structures formed by transcripts from the light strand of mtDNA.

Specifications

Catalog number
HA721076
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
G rich RNA sequence binding factor 1 antibody G rich sequence binding factor 1 antibody G-rich sequence factor 1 antibody GRSF-1 antibody GRSF1 antibody GRSF1_HUMAN antibody
Abbreviation
GRSF1
Swiss Prot
Q12849 Human
Cellular Locus
Mitochondrion matrix; Cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human GRSF1 aa 350-400/480.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell
Positive Control
Hela cell lysate, 293 cell lysate, Jurkat cell lysate, HepG2 cell lysate, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IF-Cell: 1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 53 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for GRSF1 Recombinant Rabbit Monoclonal Antibody [JE65-34]?

The catalog number for GRSF1 Recombinant Rabbit Monoclonal Antibody [JE65-34] is HA721076.

What sizes are available for GRSF1 Recombinant Rabbit Monoclonal Antibody [JE65-34]?

GRSF1 Recombinant Rabbit Monoclonal Antibody [JE65-34] is available in the following size(s): 100 µL.

Is GRSF1 Recombinant Rabbit Monoclonal Antibody [JE65-34] in stock?

GRSF1 Recombinant Rabbit Monoclonal Antibody [JE65-34] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GRSF1 Recombinant Rabbit Monoclonal Antibody [JE65-34] used for?

The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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