UCHL5IP Recombinant Rabbit Monoclonal Antibody [JE65-32]

About this product

This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants. Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium. MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake. HAUS7 (HAUS Augmin Like Complex Subunit 7) is a Protein Coding gene. Diseases associated with HAUS7 include Vas Deferens, Congenital Bilateral Aplasia Of. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Organelle biogenesis and maintenance. Gene Ontology (GO) annotations related to this gene include thioesterase binding. Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.

Specifications

Catalog number

HA721077

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

26S proteasome-associated UCH interacting protein 1 antibody 26S proteasome-associated UCH37-interacting protein 1 antibody Expressed-Xq28STS protein antibody HAUS augmin-like complex subunit 7 antibody Haus7 antibody HAUS7_HUMAN antibody HSXQ28ORF antibody UCH37 interacting protein 1 antibody UCHL5 interacting protein antibody UCHL5-interacting protein antibody UCHL5IP antibody UIP1 antibody X-linked protein STS1769 antibody

Abbreviation

HAUS7

Swiss Prot

Q99871 Human

Cellular Locus

Centrosome, spindle.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human UCHL5IP aa 150-300/368.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

293T cell lysate, Hela cell lysate, human kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:400

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 41 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes