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Product details

EMC4 Recombinant Rabbit Monoclonal Antibody [JE65-17]

Catalog number HA721082

Price for HA721082

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Size / count 100 µL

About this product

Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).

Specifications

Catalog number
HA721082
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Cell proliferation-inducing gene 17 protein antibody EMC4 antibody ER membrane protein complex subunit 4 antibody HSPC184 antibody PIG17 antibody tmem85 antibody TMM85_HUMAN antibody Transmembrane protein 85 antibody
Abbreviation
EMC4
Swiss Prot
Q5J8M3 Human, Q9CZX9 Mouse,
Cellular Locus
Endoplasmic reticulum membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human GRSF1 aa 21-70/183.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
293 cell lysate, HepG2 cell lysate, SH-SY5Y cell lysate, U87MG cell lysates, rat brain tissue lysate, rat cerebellum tissue lysate, mouse brain tissue lysate, rat brain tissue, rat cerebellum tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:5,000 ;IHC-P: 1:100-1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 20 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for EMC4 Recombinant Rabbit Monoclonal Antibody [JE65-17]?

The catalog number for EMC4 Recombinant Rabbit Monoclonal Antibody [JE65-17] is HA721082.

What sizes are available for EMC4 Recombinant Rabbit Monoclonal Antibody [JE65-17]?

EMC4 Recombinant Rabbit Monoclonal Antibody [JE65-17] is available in the following size(s): 100 µL.

Is EMC4 Recombinant Rabbit Monoclonal Antibody [JE65-17] in stock?

EMC4 Recombinant Rabbit Monoclonal Antibody [JE65-17] is currently made to order / not held in immediate stock. Contact us for lead time.

What is EMC4 Recombinant Rabbit Monoclonal Antibody [JE65-17] used for?

Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabili

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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