SAFB Recombinant Rabbit Monoclonal Antibody [JE64-94]

About this product

This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Catalog number

HA721085

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

DKFZp779C1727 antibody glutathione S transferase fusion protein antibody HAP antibody HET antibody HSP27 ERE TATA binding protein antibody HSP27 ERE-TATA-binding protein antibody HSP27 estrogen response element-TATA box-binding protein antibody SAF B antibody SAF-B antibody SAF-B1 antibody SAFB 1 antibody SAFB antibody SAFB1 antibody SAFB1_HUMAN antibody Scaffold attachment factor B1 antibody

Abbreviation

SAFB

Swiss Prot

Q15424 Human, Q80YR5 Mouse, O88453 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human SAFB aa 866-915/915.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

A431 cell lysates, 293 cell lysate, Hela cell lysate, rat brain tissue, human colon carcinoma tissue, mouse pancreas tissue, NCI-H441.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:5,000;IF-Cell: 1:50;IHC-P: 1:200-1:400

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 103 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes