PNKP Recombinant Rabbit Monoclonal Antibody [JE64-85] — image 1 of 2

Product details

PNKP Recombinant Rabbit Monoclonal Antibody [JE64-85]

Catalog number HA721087

Price for HA721087

Size / count 100 µL

About this product

Bifunctional polynucleotide phosphatase/kinase is an enzyme that in humans is encoded by the PNKP gene. A detailed structural study of the crystallized mouse protein examined both the 5´-polynucleotide kinase and 3’-polynucleotide phosphatase activities. Additional features of the peptide sequence include a forkhead association (FHA) domain, ATP binding site and nuclear and mitochondrial localization sequences. PNKP has been shown to interact with DNA polymerase beta and XRCC1. The human gene encoding PNKP was observed to be mutated in patients with microcephaly, seizures and defects in DNA repair. A type of recessive ataxia is also associated with PNKP mutations. There are also newly characterized pathological variants of PNKP. Model organisms such as mice and Drosophila have been used to generate further insights.

Specifications

Catalog number: HA721087
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 2'' (3'')-polynucleotidase antibody 2' (3')-polynucleotidase antibody Bifunctional polynucleotide phosphatase/kinase antibody DEM 1 antibody DEM1 antibody DNA 5' kinase/3' phosphatase antibody DNA 5''-kinase/3''-phosphatase antibody EIEE10 antibody Homo sapiens polynucleotide kinase 3' phosphatase (PNKP) antibody MCSZ antibody PNK 1 antibody PNK1 antibody Pnkp antibody PNKP DNA kinase antibody PNKP_HUMAN antibody Polynucleotide 3'-phosphatase antibody Polynucleotide 5' hydroxyl kinase antibody Polynucleotide 5''-hydroxyl-kinase antibody Polynucleotide kinase 3 prime phosphatase antibody Polynucleotide kinase 3' phosphatase antibody Polynucleotide Kinase antibody Polynucleotide kinase-3''-phosphatase antibody
Abbreviation: PNKP
Swiss Prot: Q96T60 Human
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within human PNKP aa 460-509/521.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HepG2 cell lysate, 293 cell lysate, PC-3 cell lysate, Jurkat cell lysate, human colon carcinoma tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 57 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for PNKP Recombinant Rabbit Monoclonal Antibody [JE64-85]?

The catalog number for PNKP Recombinant Rabbit Monoclonal Antibody [JE64-85] is HA721087.

What sizes are available for PNKP Recombinant Rabbit Monoclonal Antibody [JE64-85]?

PNKP Recombinant Rabbit Monoclonal Antibody [JE64-85] is available in the following size(s): 100 µL.

Is PNKP Recombinant Rabbit Monoclonal Antibody [JE64-85] in stock?

PNKP Recombinant Rabbit Monoclonal Antibody [JE64-85] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PNKP Recombinant Rabbit Monoclonal Antibody [JE64-85] used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.