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Product details

CYFIP1 Recombinant Rabbit Monoclonal Antibody [JE64-11]

Catalog number HA721095

Price for HA721095

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Size / count 100 µL

About this product

Cytoplasmic FMR1-interacting protein 1 is a protein that in humans is encoded by the CYFIP1 gene. CYFIP1 has been shown to interact with FMR1, to the exclusion of FXR1 and FXR2. It also forms part of the WAVE regulatory complex (WRC), and based on the crystal structure of the WRC it is believed CYFIP1 provides the binding site for the complex to Rac1.This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion.

Specifications

Catalog number
HA721095
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CY antibody CYFIP 1 antibody CYFIP1 antibody CYFP1_HUMAN antibody Cytoplasmic FMR1 interacting protein 1 antibody Cytoplasmic FMR1-interacting protein 1 antibody FLJ45151 antibody KIAA0068 antibody p140sra 1 antibody p140sra-1 antibody P140SRA1 antibody Selective hybridizing clone antibody SHYC antibody Specifically Rac1 associated protein 1 antibody Specifically Rac1-associated protein 1 antibody SRA 1 antibody Sra-1 antibody SRA1 antibody
Abbreviation
CYFIP1
Swiss Prot
Q7L576 Human, Q7TMB8 Mouse,
Cellular Locus
Cytoplasm, perinuclear region, lamellipodium, ruffle, synaptosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human CYFIP1 aa 51-100/1,253.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
SW480 cell lysate, RAW264.7 cell lysate, rat lung tissue lysate, NIH/3T3 cell lysate, rat lung tissue lysates, rat esophagus tissue, rat stomach tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:100-1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 145 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CYFIP1 Recombinant Rabbit Monoclonal Antibody [JE64-11]?

The catalog number for CYFIP1 Recombinant Rabbit Monoclonal Antibody [JE64-11] is HA721095.

What sizes are available for CYFIP1 Recombinant Rabbit Monoclonal Antibody [JE64-11]?

CYFIP1 Recombinant Rabbit Monoclonal Antibody [JE64-11] is available in the following size(s): 100 µL.

Is CYFIP1 Recombinant Rabbit Monoclonal Antibody [JE64-11] in stock?

CYFIP1 Recombinant Rabbit Monoclonal Antibody [JE64-11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CYFIP1 Recombinant Rabbit Monoclonal Antibody [JE64-11] used for?

Cytoplasmic FMR1-interacting protein 1 is a protein that in humans is encoded by the CYFIP1 gene. CYFIP1 has been shown to interact with FMR1, to the exclusion of FXR1 and FXR2. It also forms part of the WAVE regulatory complex (WRC), and based on the crystal structure of the WRC it is believed CYFI

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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