hnRNP G-T Recombinant Rabbit Monoclonal Antibody [JE64-33]

About this product

This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.

Specifications

Catalog number

HA721104

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Heterogeneous nuclear ribonucleoprotein G T antibody hnRNP G T antibody hnRNP G-T antibody HNRNPG T antibody HNRNPGT antibody HNRPGT antibody RBMX L2 antibody RBMXL 2 antibody RBMXL2 antibody RMXL2_HUMAN antibody RNA binding motif protein X linked like 2 antibody RNA-binding motif protein antibody Testes specific heterogenous nuclear ribonucleoprotein G T antibody Testis-specific heterogeneous nuclear ribonucleoprotein G-T antibody X-linked-like-2 antibody

Abbreviation

RBMXL2

Swiss Prot

O75526 Human, Q9DAE2 Mouse,

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human hnRNP G-T aa 151-350/392.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

293 cell lysate, Hela cell lysate, rat testis tissue lysates, Hela, human testis tissue, mouse testis tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:5,000;IF-Cell: 1:200;IHC-P: 1:400

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 43 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes