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Product details

PGM1 Recombinant Rabbit Monoclonal Antibody [JE65-06]

Catalog number HA721110

Price for HA721110

Size / count 100 µL

About this product

Phosphoglucomutase-1 is an enzyme that in humans is encoded by the PGM1 gene. The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red blood cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause CDG syndrome type 1t (CDG1T, formerly known as glycogen storage disease type XIV). Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Phosphoglucomutase 1 (PGM1) deficiency is an inherited metabolic disorder in humans (CDG syndrome type 1t, CDG1T). Affected patients show multiple disease phenotypes, including dilated cardiomyopathy, exercise intolerance, and hepatopathy, reflecting the central role of the enzyme in glucose metabolism.

Specifications

Catalog number: HA721110
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CDG1T antibody Glucose phosphomutase 1 antibody GSD14 antibody OTTHUMP00000010519 antibody OTTHUMP00000010520 antibody PGM 1 antibody PGM1 antibody PGM1_HUMAN antibody Phosphoglucomutase 1 antibody Phosphoglucomutase-1 antibody Phosphoglucomutase1 antibody
Abbreviation: PGM1
Swiss Prot: P36871 Human, Q9D0F9 Mouse, P38652 Rat
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human PGM1 aa 513-562/562.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: 293T cell lysate, A431 cell lysate, Hela cell lysate, HepG2 cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, rat spleen tissue lysate, mouse skeletal muscle tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 61 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for PGM1 Recombinant Rabbit Monoclonal Antibody [JE65-06]?

The catalog number for PGM1 Recombinant Rabbit Monoclonal Antibody [JE65-06] is HA721110.

What sizes are available for PGM1 Recombinant Rabbit Monoclonal Antibody [JE65-06]?

PGM1 Recombinant Rabbit Monoclonal Antibody [JE65-06] is available in the following size(s): 100 µL.

Is PGM1 Recombinant Rabbit Monoclonal Antibody [JE65-06] in stock?

PGM1 Recombinant Rabbit Monoclonal Antibody [JE65-06] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PGM1 Recombinant Rabbit Monoclonal Antibody [JE65-06] used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.