CECR5 Recombinant Rabbit Monoclonal Antibody [JE64-76]

About this product

Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.

Specifications

Catalog number

HA721120

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

A930002G03Rik antibody Cat eye syndrome chromosome region, candidate 5 antibody Cat eye syndrome chromosome region, candidate 5 homolog antibody Cat eye syndrome critical region protein 5 antibody Cecr5 antibody CECR5_HUMAN antibody MGC25951 antibody OTTMUSP00000025905 antibody

Abbreviation

HDHD5

Swiss Prot

Q9BXW7 Human

Cellular Locus

Mitochondrion.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within human CECR5 aa 351-400/423.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Hela cell lysate, HepG2 cell lysate, Jurkat cell lysate, human testis tissue, human colon tissue, human stomach tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 46 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes