RAB8A Recombinant Rabbit Monoclonal Antibody [JE64-79]

About this product

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Specifications

Catalog number

HA721127

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

AA409338 antibody MEL antibody Mel transforming oncogene (derived from cell line NK14) RAB8 homolog antibody Mel transforming oncogene (derived from cell line NK14) antibody Mel transforming oncogene (RAB8 homolog) antibody Mel transforming oncogene antibody MGC124948 antibody Oncogene c mel antibody Oncogene c-mel antibody RAB8 antibody RAB8A antibody RAB8A member RAS oncogene family antibody RAB8A_HUMAN antibody Ras associated protein RAB8 antibody Ras related protein Rab 8A antibody Ras-related protein Rab-8A antibody

Abbreviation

RAB8A

Swiss Prot

P61006 Human, P55258 Mouse, P35280 Rat

Cellular Locus

Cell membrane, golgi apparatus, recycling endosome membrane, cytoplasm, centriole, cilium basal body, cilium axoneme, cilium, phagosome, phagosome membrane, midbody.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human RAB8A aa 151-200/207.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, FC, IF-Cell, IP

Positive Control

Hela cell lysate, HepG2 cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, C2C12 cell lysate, L6 cell lysate, HeLa.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;FC: 1:500-1:1,000 ;IF-Cell: 1:100 ;IP: 1-2μg/sample

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 24 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes