RBM3 Recombinant Rabbit Monoclonal Antibody [JE63-84]

About this product

Putative RNA-binding protein 3 is a protein that in humans is encoded by the RBM3 gene. This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. RBM3 is cold-induced RNA binding protein and is involved in mRNA biogenesis exerts anti-apoptotic effects. According to antibody-based profiling and transcriptomics analysis, RBM3 protein is present in all analysed human tissues and based on confocal microscopy mainly localised to the nucleoplasm. RBM3 is a proto-oncogene that is associated with tumor progression and metastasis and is a potential cancer biomarker. Based on patient survival data, high levels of RBM3 protein in tumor cells is a favourable prognostic biomarker in colorectal cancer.

Specifications

Catalog number

HA721130

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

2600016C11Rik antibody IS1 RNPL antibody MGC105811 antibody MGC118410 antibody OTTHUMP00000025800 antibody OTTHUMP00000025802 antibody OTTMUSP00000019634 antibody OTTMUSP00000019635 antibody OTTMUSP00000019636 antibody Putative RNA binding protein 3 antibody Putative RNA-binding protein 3 antibody Rbm3 antibody RBM3_HUMAN antibody RNA binding motif (RNP1, RRM) protein 3 antibody RNA binding motif protein 3 antibody RNA-binding motif protein 3 antibody RNA-binding protein 3 antibody RNPL antibody RP23-27I6.7 antibody

Abbreviation

RBM3

Swiss Prot

P98179 Human, O89086 Mouse, Q925G0 Rat

Cellular Locus

Nucleus, cytoplasm, dendrite.

Host

Rabbit

Species Reactivity

Mouse, Human, Rat

Immunogen

Recombinant protein within human RBM3 aa 58-157/157.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

IF-Cell, IHC-P, FC

Positive Control

Hela, human esophagus tissue, mouse thyroid tissue, mouse trachea tissue, rat trachea tissue, rat esophagus tissue, THP-1.

Concentration

1 mg/mL

Dilution

IF-Cell: 1:50;IHC-P: 1:400;FC: 1:500-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 17 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes