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Product details

TGF beta 1 Recombinant Rabbit Monoclonal Antibody [PD00-17]

Catalog number HA721143

Discontinued

Price for HA721143

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Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. In humans, TGF-β1 is encoded by the TGFB1 gene. TGF-β is a multifunctional set of peptides that controls proliferation, differentiation, and other functions in many cell types. TGF-β acts synergistically with transforming growth factor-alpha (TGF-α) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGF-β activation and signaling may result in apoptosis. Many cells synthesize TGF-β and almost all of them have specific receptors for this peptide. TGF-β1, TGF-β2, and TGF-β3 all function through the same receptor signaling systems. TGF-β1 was first identified in human platelets as a protein with a molecular mass of 25 kilodaltons with a potential role in wound healing. It was later characterized as a large protein precursor (containing 390 amino acids) that was proteolytically processed to produce a mature peptide of 112 amino acids. TGF-β1 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Most immune cells (or leukocytes) secrete TGF-β1.

Specifications

Catalog number
HA721143
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
Product Name Alternative
Cartilage-inducing factor antibody CED antibody Differentiation inhibiting factor antibody DPD1 antibody LAP antibody Latency-associated peptide antibody Prepro transforming growth factor beta 1 antibody TGF beta 1 antibody TGF beta antibody TGF beta 1 protein antibody TGF-beta 1 protein antibody TGF-beta-1 antibody TGF-beta-5 antibody TGF-beta1 antibody TGFB antibody Tgfb-1 antibody tgfb1 antibody TGFB1_HUMAN antibody TGFbeta antibody TGFbeta1 antibody Transforming Growth Factor b1 antibody Transforming Growth Factor beta 1 antibody Transforming growth factor beta 1a antibody transforming growth factor beta-1 antibody transforming growth factor, beta 1 antibody Transforming Growth Factor-ß1 antibody
Abbreviation
TGFB1
Swiss Prot
P01137 Human, P04202 Mouse, P17246 Rat
Cellular Locus
Extracellular matrix, Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide (KLH-coupled) corresponding to Human TGF-Beta 1 C-terminal.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue
Positive Control
Raji cell lysate, K-562 cell lysate, Mouse spleen tissue lysate, Rat spleen tissue lysate, A549 cell lysate, L-929 cell lysate, NIH/3T3 cell lysate, rat spleen tissue, mouse spleen tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:200 ;IF-Tissue: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for TGF beta 1 Recombinant Rabbit Monoclonal Antibody [PD00-17]?

The catalog number for TGF beta 1 Recombinant Rabbit Monoclonal Antibody [PD00-17] is HA721143.

Is TGF beta 1 Recombinant Rabbit Monoclonal Antibody [PD00-17] in stock?

TGF beta 1 Recombinant Rabbit Monoclonal Antibody [PD00-17] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TGF beta 1 Recombinant Rabbit Monoclonal Antibody [PD00-17] used for?

Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. In human

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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