Arginase-1 Recombinant Rabbit Monoclonal Antibody [PD00-05]

Catalog number HA721147

Price for HA721147

Size / count 100 µL

About this product

Arginase-1 is a key urea cycle metalloenzyme that has demonstrated expression in normal human liver with a high degree of specificity. Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver accounting for an estimated 70%-85% of total liver cancers worldwide. Diagnostic pitfalls exist in the morphologic distinction of HCC from other hepatocellular and non-hepatocellular lesions. In difficult or equivocal cases, the application of immunohistochemical (IHC) panels has been shown to aid in the distinction of benign and malignant liver lesions. In sections of normal liver, anti-arginase-1 produced strong, diffuse cytoplasmic reactivity in all hepatocytes throughout the lobule. In some cases, patchy nuclear reactivity is also evident in hepatocytes along with the cytoplasmic reactivity. Reactivity is not observed in bile duct epithelial cells, sinusoidal endothelial cells, Kupffer cells, or vascular endothelial cells. In sections of HCC, anti-arginase-1 produces cytoplasmic or cytoplasmic plus nuclear reactivity.

Specifications

Catalog number: HA721147
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: A I antibody Al antibody ARG 1 antibody arg1 antibody ARGI1_HUMAN antibody Arginase 1 antibody Arginase liver antibody Arginase type I antibody Arginase, liver antibody Arginase-1 antibody Arginase1 antibody Liver type arginase antibody Liver-type arginase antibody Type I arginase antibody
Abbreviation: ARG1
Swiss Prot: P05089 Human
Cellular Locus: Cytoplasm, Cytoplasmic granule.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human Liver Arginase (C terminal)
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Human liver tissue lysates, human liver tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:1,000-1:5,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 35 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Arginase-1 Recombinant Rabbit Monoclonal Antibody [PD00-05]?

The catalog number for Arginase-1 Recombinant Rabbit Monoclonal Antibody [PD00-05] is HA721147.

What sizes are available for Arginase-1 Recombinant Rabbit Monoclonal Antibody [PD00-05]?

Arginase-1 Recombinant Rabbit Monoclonal Antibody [PD00-05] is available in the following size(s): 100 µL.

Is Arginase-1 Recombinant Rabbit Monoclonal Antibody [PD00-05] in stock?

Arginase-1 Recombinant Rabbit Monoclonal Antibody [PD00-05] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Arginase-1 Recombinant Rabbit Monoclonal Antibody [PD00-05] used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.