KDM3B Recombinant Rabbit Monoclonal Antibody [1A8]

Catalog number HA721170

Price for HA721170

Size / count 100 µL

About this product

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. Its gene is located in the 5q region of the genome which is deleted in del (5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del (5q) tumor suppressor gene. A multitude of publications have implicated JMJD1A as a driver of tumorigenesis in a variety of different cancers. Less evidence hints at JMJD1B and JMJD1C as potential oncogenic proteins. And there is persuasive data to suggest that JMJD1B is a tumor suppressor, especially in AML, and JMJD1A and JMJD1C may also be tumor suppressive in germ cell tumors. Tissue specificity: Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.

Specifications

Catalog number: HA721170
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 5qNCA antibody C5orf7 antibody JHDM2B antibody JmjC domain containing histone demethylation protein 2B antibody JmjC domain-containing histone demethylation protein 2B antibody jmjd1b antibody Jumonji domain containing 1B antibody Jumonji domain containing protein 1B antibody Jumonji domain-containing protein 1B antibody KDM3B antibody KDM3B_HUMAN antibody KIAA1082 antibody Lysine (K) specific demethylase 3B antibody Lysine-specific demethylase 3B antibody NET22 antibody Nuclear protein 5qNCA antibody
Abbreviation: Lysine-specific demethylase 3B JmjC domain-containing histone demethylation protein 2B Jumonji domain-containing protein 1B Nuclear protein 5qNCA [histone H3]-dimethyl-L-lysine (9) demethylase 3B KDM3B C5orf7 JHDM2B JMJD1B KIAA1082
Swiss Prot: Q7LBC6 Human, Q6ZPY7 Mouse
Cellular Locus: Nucleus
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human KDM3B aa 251-500.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Cell, FC
Positive Control: Hela cell lysate, NIH/3T3 cell lysate, Hela, human testis tissue, human fallopian tube tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000;IF-Cell: 1:100;IHC-P: 1:400-1:2,000;FC: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 191 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for KDM3B Recombinant Rabbit Monoclonal Antibody [1A8]?

The catalog number for KDM3B Recombinant Rabbit Monoclonal Antibody [1A8] is HA721170.

What sizes are available for KDM3B Recombinant Rabbit Monoclonal Antibody [1A8]?

KDM3B Recombinant Rabbit Monoclonal Antibody [1A8] is available in the following size(s): 100 µL.

Is KDM3B Recombinant Rabbit Monoclonal Antibody [1A8] in stock?

KDM3B Recombinant Rabbit Monoclonal Antibody [1A8] is currently made to order / not held in immediate stock. Contact us for lead time.

What is KDM3B Recombinant Rabbit Monoclonal Antibody [1A8] used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

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Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.