Stathmin Recombinant Rabbit Monoclonal Antibody [PD00-54]

About this product

Stathmin, also known as oncoprotein 18 (Op18), is a ubiquitously expressed 19 kDa cytosolic phosphoprotein responsible for integrating various cellular regulatory signals. Stathmin has been implicated in both G1-S and G2-M checkpoint control of cell cycle progression and plays a major role in cell proliferation, differentiation, development and morphogenesis. Overexpression of Stathmin has been associated with tumor progression in endometrial carcinomas, ovarian carcinoma and oral squamous cell carcinoma. A recent study by Howitt et al. on 193 cervical lesions demonstrated that Stathmin was positive in 5/56 (9%) CIN1, 5/11 (45%) CIN2, 14/15 (93%) CIN3 cases of cervical intraepithelial neoplasias; and all of adenocarcinoma in situ (19/19), invasive squamous cell carcinoma (32/32) and adenocarcinoma (34/34) cases. It is valuable to distinguish CIN3 from the majority of low-grade precursors and negative/reactive cervical biopsies.

Specifications

Catalog number

HA721179

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

C1orf215 antibody Lag antibody LAP 18 antibody LAP18 antibody Leukemia associated phosphoprotein p18 antibody Leukemia-associated phosphoprotein p18 antibody Metablastin antibody Oncoprotein 18 antibody OP 18 antibody Op18 antibody p18 antibody p19 antibody Phosphoprotein 19 antibody Phosphoprotein p19 antibody pp17 antibody pp19 antibody PR22 antibody Pr22 protein antibody Prosolin antibody Protein Pr22 antibody SMN antibody Stathmin antibody Stathmin1 antibody STMN 1 antibody Stmn1 antibody STMN1_HUMAN antibody

Abbreviation

Stathmin Leukemia-associated phosphoprotein p18 Metablastin Oncoprotein 18 Op18 Phosphoprotein p19 pp19 Prosolin Protein Pr22 pp17 STMN1 C1orf215 LAP18 OP18

Swiss Prot

P16949 Human, P54227 Mouse, P13668 Rat

Cellular Locus

Cytoskeleton

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human Stathmin 1 aa 100 to the C-terminus (internal sequence).

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

IHC-P, WB, IF-Cell, IF-Tissue, FC

Positive Control

HeLa cell tissue lysate, SH-SY5Y cell tissue lysate, Jurkat cell tissue lysate, Mouse brain tissue lysate, Rat brain tissue lysate, human breast cancer tissue, human colon cancer tissue, human endometrial carcinoma tissue, human tonsil tissue, human liver tissue, Jurkat, mouse brain tissue, rat brain tissue.

Concentration

1 mg/mL

Dilution

IHC-P: 1:2,000-1:5,000 ;WB: 1:1,000 ;IF-Cell: 1:1,000 ;IF-Tissue: 1:500 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 17 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes