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Product details

Tcl1 Recombinant Rabbit Monoclonal Antibody [PD00-94]

Catalog number HA721207

Price for HA721207

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Size / count 100 µL

About this product

T-cell leukemia/lymphoma protein 1A (TCL1) is a member of the TCL1 family and enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. TCL1 promotes the nuclear translocation of AKT1 and enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. The expression of TCL1 is restricted to lymphoid cells. It is expressed early in lymphocyte differentiation. Strong expression of TCL1 is found in a subset of mantle zone B lymphocytes and is expressed to a lesser extent by follicle center cells. In B-cell neoplasia, TCL1 immunoreactivity is found in the majority of B-cell lymphomas including lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, Burkitt lymphoma, diffuse large B-cell lymphoma (60%), and primary cutaneous B-cell lymphoma (55%). The expression of the TCL1 gene characterizes low-grade B-cell lymphomas.

Specifications

Catalog number
HA721207
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Anti TCL1A antibody Lymphoma/leukemia, T-cell antibody Oncogene TCL-1 antibody Oncogene TCL1 antibody P14 TCL1 antibody P14 TCL1 protein antibody Protein p14 TCL1 antibody T cell leukemia 1 antibody T cell lymphoma 1 antibody T cell lymphoma 1A antibody T-cell leukemia/lymphoma 1A antibody T-cell leukemia/lymphoma protein 1A antibody TCL 1 protein antibody TCL1 antibody TCL1 oncogene antibody TCL1 PEN antibody Tcl1a antibody TCL1A antibody antibody TCL1A_HUMAN antibody
Abbreviation
TCL1A, TCL1
Swiss Prot
P56279 Human
Cellular Locus
Cytoplasm, Nucleus, Microsome, Endoplasmic reticulum.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human Tcl1 aa 1-114.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
Daudi cell lysate, Raji cell lysate, human tonsil tissue, human appendix tissue, PC-3, Daudi.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:2,000 ;IF-Cell: 1:50 ;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 13 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Tcl1 Recombinant Rabbit Monoclonal Antibody [PD00-94]?

The catalog number for Tcl1 Recombinant Rabbit Monoclonal Antibody [PD00-94] is HA721207.

What sizes are available for Tcl1 Recombinant Rabbit Monoclonal Antibody [PD00-94]?

Tcl1 Recombinant Rabbit Monoclonal Antibody [PD00-94] is available in the following size(s): 100 µL.

Is Tcl1 Recombinant Rabbit Monoclonal Antibody [PD00-94] in stock?

Tcl1 Recombinant Rabbit Monoclonal Antibody [PD00-94] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Tcl1 Recombinant Rabbit Monoclonal Antibody [PD00-94] used for?

T-cell leukemia/lymphoma protein 1A (TCL1) is a member of the TCL1 family and enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. TCL1 promotes the nuclear translocation of AKT1 and enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. T

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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