TNS4 Recombinant Rabbit Monoclonal Antibody [PD00-95]

Catalog number HA721208

Price for HA721208

Size / count 100 µL

About this product

TNS4, as the others tensins, contains a phosphotyrosine-binding domain (PTB), which plays the role of interacting with the cytoplasmic tail of the β-integrin. Also TNS4 is found to play a central role in HGF-induced tubulogenesis. The role of TNS4 on cell proliferation is found to be minimal and not up to the level of the effect of migration. By enhancing the motility and having the effect on the tubulogenesis, TNS4 is believed to have a role in cancer cell metastasis. The role of cten in cancer is not well defined. In prostate cancer it is down-regulated, where in normal cells it is localized to focal adhesions recruiting the tumour suppressor, deleted in liver cancer (DLC-1), thus suppressing tumorigenesis. Cten in prostate epithelial cells has also been found to regulate staurosporine-induced apoptosis where cten is cleaved by caspase 3 and results in reduction in cell growth rate. Therefore, loss of cten expression may lead to uncontrolled cell growth and result in cell transformation. Accordingly, in prostate cancer, cten may function as a tumour suppressor protein.

Specifications

Catalog number: HA721208
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: C terminal tensin like antibody C terminal tensin like protein antibody C-terminal tensin-like protein antibody CTEN antibody FLJ14950 antibody PP14434 antibody TENS4_HUMAN antibody Tensin 4 antibody Tensin-4 antibody Tns4 antibody
Abbreviation: TNS4, CTEN,
Swiss Prot: Q8IZW8 Human
Cellular Locus: Cell junction, focal adhesion, Cytoplasm, cytoskeleton.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human TNS4/CTEN aa 700 to the C-terminus (C terminal).
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: IHC-P
Positive Control: Human liver carcinoma tissue, human placenta tissue.
Concentration: 1 mg/mL
Dilution: IHC-P: 1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 77 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TNS4 Recombinant Rabbit Monoclonal Antibody [PD00-95]?

The catalog number for TNS4 Recombinant Rabbit Monoclonal Antibody [PD00-95] is HA721208.

What sizes are available for TNS4 Recombinant Rabbit Monoclonal Antibody [PD00-95]?

TNS4 Recombinant Rabbit Monoclonal Antibody [PD00-95] is available in the following size(s): 100 µL.

Is TNS4 Recombinant Rabbit Monoclonal Antibody [PD00-95] in stock?

TNS4 Recombinant Rabbit Monoclonal Antibody [PD00-95] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TNS4 Recombinant Rabbit Monoclonal Antibody [PD00-95] used for?

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.