VPAC1 Recombinant Rabbit Monoclonal Antibody [PD00-96]

About this product

There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2. These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide (PACAP) to some degree. Both receptors are members of the 7 transmembrane G protein-coupled receptor family. VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes. VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) receptors are activated by the endogenous peptides VIP, PACAP-38, PACAP-27, peptide histidine isoleucineamide (PHI), peptide histidine methionineamide (PHM) and peptide histidine valine (PHV). Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.

Specifications

Catalog number

HA721209

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

FLJ41949 antibody HVR 1 antibody HVR1 antibody PACAP R 2 antibody PACAP type II receptor antibody PACAP-R-2 antibody PACAP-R2 antibody Pituitary adenylate cyclase activating polypeptide receptor type II antibody Pituitary adenylate cyclase activating polypeptide type II receptor antibody Pituitary adenylate cyclase-activating polypeptide type II receptor antibody RCD1 antibody RDC 1 antibody RDC1 antibody V1RG antibody VAPC 1 antibody VAPC1 antibody Vasoactive intestinal peptide receptor 1 antibody Vasoactive intestinal polypeptide receptor 1 antibody Vasoactive intestinal polypeptide receptor 1 precursor antibody VIP and PACAP receptor 1 antibody VIP R 1 antibody VIP receptor type I antibody VIP-R-1 antibody VIPR 1 antibody VIPR antibody VIPR1 antibody VIPR1_HUMAN antibody VIRG antibody VPAC 1 antibody VPAC1 antibody VPCAP1R antibody

Abbreviation

VIPR1

Swiss Prot

P32241 Human, P97751 Mouse, P30083 Rat

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Synthetic peptide within human VIPR1 aa 400-457.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

IHC-P, WB

Positive Control

HeLa cell lysate, Jurkat cell lysate, Raji cell lysate, HT-29 cell lysate, Caco-2 cell lysate, MCF7 cell lysate, MDA-MB-231 cell lysate, PC-12 cell lysate, LNCaP cell lysate, human tonsil tissue, NIH/3T3 cell lysate, C2C12 cell lysate, COS-1 cell lysate, C6 cell lysate, L6 cell lysate, mouse liver tissue lysate, mouse lung tissue lysate, mouse small intestine tissue lysate, mouse colon tissue lysate, rat lung tissue lysate, rat liver tissue lysate, human liver tissue, mouse liver tissue, rat liver tissue, rat spleen tissue.

Concentration

1 mg/mL

Dilution

IHC-P: 1:500-1:4,000 ;WB: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 52 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes