Product details
Catalog number HA721221
Price for HA721221
Size / count 100 µL
Pancreatic secretory trypsin inhibitor (PSTI) also known as serine protease inhibitor Kazal-type 1 (SPINK1) or tumor-associated trypsin inhibitor (TATI) is a protein that in humans is encoded by the SPINK1 gene. Mutations in SPINK1 has been associated with hereditary pancreatitis and tropical pancreatitis. Trypsinogen is normally created and stored an inactive zymogen of trypsin in the pancreas, but occasionally will autoactivate itself. PSTI serves to cleave prematurely activated trypsin to prevent the enzyme from causing cellular damage to the organ. Without the function of PSTI, the pancreas is subject to repeated episodes of damage. p.N34S mutation leads to idiopathic pancreatitis (for those reading zarovizsga). It has also been associated with prostate cancer.
The catalog number for SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93] is HA721221.
SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93] is available in the following size(s): 100 µL.
SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93] is currently made to order / not held in immediate stock. Contact us for lead time.
Pancreatic secretory trypsin inhibitor (PSTI) also known as serine protease inhibitor Kazal-type 1 (SPINK1) or tumor-associated trypsin inhibitor (TATI) is a protein that in humans is encoded by the SPINK1 gene. Mutations in SPINK1 has been associated with hereditary pancreatitis and tropical pancre
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.