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Product details

SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93]

Catalog number HA721221

Price for HA721221

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Size / count 100 µL

About this product

Pancreatic secretory trypsin inhibitor (PSTI) also known as serine protease inhibitor Kazal-type 1 (SPINK1) or tumor-associated trypsin inhibitor (TATI) is a protein that in humans is encoded by the SPINK1 gene. Mutations in SPINK1 has been associated with hereditary pancreatitis and tropical pancreatitis. Trypsinogen is normally created and stored an inactive zymogen of trypsin in the pancreas, but occasionally will autoactivate itself. PSTI serves to cleave prematurely activated trypsin to prevent the enzyme from causing cellular damage to the organ. Without the function of PSTI, the pancreas is subject to repeated episodes of damage. p.N34S mutation leads to idiopathic pancreatitis (for those reading zarovizsga). It has also been associated with prostate cancer.

Specifications

Catalog number
HA721221
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ISK1_HUMAN antibody Pancreatic secretory trypsin inhibitor antibody Pancreatic serine protease inhibitor Kazal antibody PCTT antibody PSTI antibody Serine protease inhibitor Kazal type 1 antibody Serine protease inhibitor Kazal-type 1 antibody Spink 3 antibody SPINK1 antibody Spink3 antibody TaTI antibody TCP antibody Tumor associated trypsin inhibitor antibody Tumor-associated trypsin inhibitor antibody
Abbreviation
SPINK1
Swiss Prot
P00995 Human
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant full length protein corresponding to Human SPINK1/P12 aa 1 to the C-terminus.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
IHC-P
Positive Control
Human pancreas tissue.
Concentration
1 mg/mL
Dilution
IHC-P: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 9 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93]?

The catalog number for SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93] is HA721221.

What sizes are available for SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93]?

SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93] is available in the following size(s): 100 µL.

Is SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93] in stock?

SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SPINK1 Recombinant Rabbit Monoclonal Antibody [PD00-93] used for?

Pancreatic secretory trypsin inhibitor (PSTI) also known as serine protease inhibitor Kazal-type 1 (SPINK1) or tumor-associated trypsin inhibitor (TATI) is a protein that in humans is encoded by the SPINK1 gene. Mutations in SPINK1 has been associated with hereditary pancreatitis and tropical pancre

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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