Human IL-4 Recombinant Rabbit Monoclonal Antibody [PS00-66] - BSA and Azide free (Detector)

Catalog number HA721231

Price for HA721231

Size / count 100 µL

About this product

Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1. Regulates also the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. In addition, plays a critical role in higher functions of the normal brain, such as memory and learning. Upon binding to IL4, IL4R receptor dimerizes either with the common IL2R gamma chain/IL2RG to produce the type 1 signaling complex, located mainly on hematopoietic cells, or with the IL13RA1 to produce the type 2 complex, which is expressed also on nonhematopoietic cells. Engagement of both types of receptors initiates JAK3 and to a lower extend JAK1 phosphorylation leading to activation of the signal transducer and activator of transcription 6/STAT6.

Specifications

Catalog number: HA721231
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: B cell growth factor 1 antibody B cell IgG differentiation factor antibody B Cell Stimulatory Factor 1 antibody B-cell stimulatory factor 1 antibody BCGF 1 antibody BCGF1 antibody Binetrakin antibody BSF-1 antibody BSF1 antibody IGG1 induction factor antibody IL 4 antibody IL-4 antibody IL4 antibody IL4_HUMAN antibody Il4e12 antibody Interleukin 4 antibody Interleukin 4 variant 2 antibody Interleukin 4, isoform 1 antibody Interleukin-4 antibody Lymphocyte stimulatory factor 1 antibody MGC79402 antibody Pitrakinra antibody
Abbreviation: Interleukin-4 IL4 IL-4 B-cell stimulatory factor 1 (BSF-1) Binetrakin Lymphocyte stimulatory factor 1 Pitrakinra
Swiss Prot: P05112 Human
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant full length protein.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: ELISA (Det)
Positive Control: Recombinant IL-4 protein.
Concentration: 1 mg/mL
Dilution: ELISA (Det): Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4).
Molecular Weight: Predicted band size: 17.5 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Human IL-4 Recombinant Rabbit Monoclonal Antibody [PS00-66] - BSA and Azide free (Detector)?

The catalog number for Human IL-4 Recombinant Rabbit Monoclonal Antibody [PS00-66] - BSA and Azide free (Detector) is HA721231.

What sizes are available for Human IL-4 Recombinant Rabbit Monoclonal Antibody [PS00-66] - BSA and Azide free (Detector)?

Human IL-4 Recombinant Rabbit Monoclonal Antibody [PS00-66] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Human IL-4 Recombinant Rabbit Monoclonal Antibody [PS00-66] - BSA and Azide free (Detector) in stock?

Human IL-4 Recombinant Rabbit Monoclonal Antibody [PS00-66] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human IL-4 Recombinant Rabbit Monoclonal Antibody [PS00-66] - BSA and Azide free (Detector) used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.